Effect of Blood Pressure on Intraocular Pressure in Primary Open Angle Glaucoma
Purpose: To determine the effect of change in blood pressure on intraocular pressure in primary open angle glaucoma patients coming to a tertiary care hospital.
Study Design: Cross sectional descriptive study.
Place and Duration of study: Ophthalmology department Karachi Medical and Dental College Abbasi Shaheed Hospital from January 2015-June 2016
Material and Methods: Patients were registered through non probability consecutive sampling technique. Patients with Primary open angle glaucoma were included, secondary and angle closure glaucoma were excluded. Intraocular pressure and blood pressure was recorded. Data was collected and analyzed by using Statistical Package for Social Sciences (SPSS 21). Kruskal Wallis test was used to compare systolic blood pressure with median intraocular pressure of both eyes. Mann Whitney test was used to compare diastolic blood pressure with median intra ocular pressure of both eyes.
Results: There were 379 patients with mean age of 59.68 ± 11.37 SD. Males were 188 (49.6%). Mean IOP of right eye was 18.00 mm Hg ± 5.81 and left eye was 19 mm Hg ±
5.87. The median difference in inter quartile range (IQR) of IOP with Systolic blood pressure category > 140 mm Hg was 18 (16 – 19) mm Hg for right eye (p<0.001) was statistically significant. The median difference in IQR of IOP at diastolic blood pressure category 90–110 mm Hg was 18 (16 – 22) mm Hg for right eye and was also statistically significant. Median IQR of IOP right and left eye in males were statistically not significant as compared to females (0.908 & 0.978)
Conclusion: The intraocular pressure in primary open angle glaucoma patients increased with increase in blood pressure.
Key Words: Primary Open Angle Glaucoma, Diastolic blood pressure, Systolic blood pressure, intraocular pressure.