Amniotic Membrane Transplantation in Ocular Surface Disorders

Abstract

Purpose: To evaluate the usefulness of amniotic membrane in the patients with ocular surface diseases.

Material and Methods: This case series study of one year duration was conducted in Institute of Ophthalmology, Mayo Hospital Lahore. 30 patients having ocular surface disorders were treated with amniotic membrane transplant (AMT) and improvement in the signs and symptoms of ocular irritation like pain, photophobia was evaluated.

Results: Out of 30 patients 18 (60%) were male and 12 (40 %) female. Ocular surface disorders include 8 (26.7%) cases of bullous keratopathy, 5 (16.7%) Mooren’s ulcer, 5 (16.7%) Shabbir syndrome, 4(13.3%) impending perforations, 3 (10.0%) Chemical injury, 3 (10%) Steven Johnson syndrome and 2 (6.7%) cases of neurotrophic ulcer. More than 90% of the cases after AMT showed remarkable improvement in the symptoms of ocular irritation.

Conclusion: Amniotic membrane is a useful material for the treatment of ocular surface disorders.