Corneal Endothelial Cell Loss after Phacoemulsification with and without Trypan Blue ? 218 Assisted Staining of Anterior Lens Capsule

Abstract

PURPOSE:

To study the mean loss of corneal endothelial cell in patients undergoing

cataract surgery with phacoemulsification with and without trypan blue.

STUDY DESIGN:

Randomized controlled trial

PLACE  AND DURATION OF STUDY:

Institute of Ophthalmology, Mayo Hospital/ King Edward Medical University,

Lahore.

From 1-1-2016 to 30-5-2017

MATERIAL AND METHODS:

152 patients presenting to the Institute of Ophthalmology were included in

study. Patients diagnosed with cataract were selected for surgery. The

patients were divided into two groups A and B. Group A patients underwent

phacoemulsification with trypan blue aided central curvilinear capsulorhexis

while Group B patients underwent phacoemulsification without any aid of

trypan blue. Patients with any corneal opacity were excluded from study.

Specular microscopy was done on all patients before and three months after

surgery. On specular microscopy, corneal endothelial count, hexagonality

and coefficient of variation were noted. Specular microscopy and recording

of findings was done by researcher.

RESULTS:

Endothelial cell loss was observed in both the groups but it was more

in the Group A (74.3421±0.6332)as compared to the Group B

(37.0658±2.6891) (p 0.000).

CONCLUSION:

Phacoemulsification decreases corneal endothelial cell count both with and

without trypan blue. The decrease in corneal endothelial cell count was more

when phacoemulsification was done with trypan blue but it did not lead to

corneal decompensation.

KEY WORDS:

Phacoemulsification, Trypan Blue, Corneal Endothelial Cell Count.