Control of Raised Intraocular Pressure after Intravitreal Triamcinolone Acetonide

Authors

  • P. S. Mahar, A. Sami Memon

DOI:

https://doi.org/10.36351/pjo.v30i3.219

Abstract

Purpose: To determine the various treatment options including anti-glaucoma
medication, laser and surgery to control the intraocular pressure (IOP) rise after
Intravitreal triamcinolone acetonide (IVTA).
Material and Methods: This prospective, interventional case series was carried
out at Isra Postgraduate Institute of Ophthalmology, Karachi from May 2007 to
April 2009. Patients with various choroidal and retinal vascular disorders, who
were given IVTA in a dose of 4 mg / 0.1 ml and developed raised IOP ( > 21 mm
Hg) were included in the study and followed up for one year.
Results: Two hundred thirty seven eyes of 180 patients received IVTA during
the study period. The mean age of patients was 50.86 ± 10.62 years with gender
distribution of 99 male and 81 female. One hundred seventeen (49.36%) out of
237 eyes showed raised IOP after IVTA. Fifty two (21.94%) eyes showed an IOP
between 25-30 mmHg while 65 (27.42%) had IOP of > 30 mm Hg. Successful
control of IOP was defined as an IOP of less than 21 mm Hg. Thirty-four
(29.05%) eyes were controlled with single beta-blocker therapy (Timolol maleate
0.5%) and 69 (58.97%) eyes were brought into control with combination therapy
(Timolol maleate 0.5% + Dorzolamide 2%). Additional 4 (3.41%) eyes required
Prostaglandin analogue (Latanoprost 0.005%) along with combination therapy
for IOP control. Another 4 (3.41%) eyes were controlled with Argon laser
trabeculoplasty and full medical treatment and remaining 6 (5.12%) eyes settled
down with trabeculectomy with adjunctive mitomycin-C.
Conclusion: Although IVTA is a cost-effective therapeutic agent against various
choroidal and retinal disorders, 50% of the patients developed raised IOP > 21
mm Hg. Half of these patients required multiple drugs and almost 5% needed
surgical intervention to control IOP under 21 mm Hg.
Key words: Triamcinolone acetonide, Intraocular pressure, Glaucoma.

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Published

30-09-2014

How to Cite

1.
A. Sami Memon PSM. Control of Raised Intraocular Pressure after Intravitreal Triamcinolone Acetonide. pak J Ophthalmol [Internet]. 2014 Sep. 30 [cited 2024 Mar. 28];30(3). Available from: https://pjo.org.pk/index.php/pjo/article/view/219

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Section

Review Articles