Pain Perception during Laser in Situ Keratomileusis

  • Sharmeen Akram, Salman Naveed Sadiq , Khabir Ahmad


Purpose: To compare pain severity during laser in situ keratomileusis (LASIK)
between first- and second – eye surgery in a Pakistani population.
Material and Methods: This was a prospective cohort study. 31 individuals
eligible for LASIK in both eyes were recruited at a laser clinic between June
2012 and November 2015. All underwent surgery using microkeratome and
CustomVis Solid state laser. After completion of the procedure, patients rated
severity of their pain during Lasik on a 4 – point scale (e.g. none, mild, moderate,
severe pain) for each eye separately. Wilcoxon signed – rank test was used to
compare pain severity between first- and second – eye surgery.
Results: A total of 31 patients (62 eyes) were enrolled in the study. 16 (51.6%)
patients perceived more pain in the second eye and 6 (19.4%) in the first one.
There were 9 (29.0%) ties. The Wilcoxon signed – rank test showed a statistically
significant change in pain perception in the second eye (Z =-2.343; P = 0.019).
Conclusions: Patients undergoing LASIK perceived more pain in the second
eye. Larger studies are needed to investigate this finding further, and to identify
factors influencing this change in pain perception.

How to Cite
, Khabir Ahmad SASNS. Pain Perception during Laser in Situ Keratomileusis. pjo [Internet]. 31Dec.2015 [cited 25Sep.2021];31(4). Available from:
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