TY - JOUR AU - Arshad Ali, Noman Ahmed, Munawar Ahmed, M. Arshad Mahmood, Aif Mansoor Ahmed Murtaza Sameen, PY - 2015/12/31 Y2 - 2024/03/29 TI - Role of Topical Travoprost in Non Syndromic (simple) Axial Myopia in Young Persons JF - Pakistan Journal of Ophthalmology JA - pak J Ophthalmol VL - 31 IS - 4 SE - Review Articles DO - 10.36351/pjo.v31i4.189 UR - https://pjo.org.pk/index.php/pjo/article/view/189 SP - AB - <p>Purpose: To evaluate the role of topical Travoprost 0.004% eye drops in<br>reducing simple axial myopia in young patients.<br>Material and Methods: This case and control study was conducted on 45 young<br>patients of either sex from 18 to 25 years old, who were selected by independent<br>random sampling technique. Patients having best corrected visual acuity of 6/6<br>in both eyes, axial length more than 24 mm, myopia of -1.0 D to -4.0 D, and<br>intraocular pressure of 16 to 20 mm Hg were registered for the study. After<br>informed consent, slit lamp examination of anterior and posterior segment was<br>done. Intra-ocular pressure and axial length were measured. Travoprost .004%<br>eye drops were used in one eye once daily in the evening for four months. The<br>fellow eye was kept as control. Follow up was done every month up to six<br>months. On each visit best corrected visual acuity, axial length, and IOP were<br>examined. Any complaint or complication was also noted and results were<br>compiled.<br>Results: In these forty five patients reduction of myopia in treated eye was seen<br>in 24 (53.33%), stabilization of myopia in 13 (28.88%), and increase in myopia<br>was seen in 08(17.77%) patients. In these patients IOP 7.2445 mm Hg, axial<br>length 0.2089 mm, and myopia -0.4444 D was reduced (P-value less than .05,<br>as compared to fellow control eye where axial length and myopia increased by<br>0.1423 mm and -0.0478 D respectively. Despite IOP decreased by 1.0889 mm<br>Hg. P-value was again less than .05. Temporary headache in 8 (17.77%),<br>Conjunctival congestion in 16(35%) patients. Complication of darkening and<br>lengthening of lashes were noted to variable degree in all treated eyes.<br>Conclusions: Topical Travoprost 0.004% eye drops is effective in reducing axial<br>myopia in young persons.<br>Key words: Myopia, refraction, axial length, IOP, Travoprost eye drops, Young<br>patients.</p> ER -