TY - JOUR AU - Shaikh, Kaleemullah AU - Ahmed, Nasir AU - Kazi, Umer AU - Zia, Ali AU - Aziz, Muhammad Zunair PY - 2022/12/31 Y2 - 2024/03/29 TI - Comparison between Suprachoroidal Triamcinolone and Intravitreal Triamcinolone Acetonide in patients of resistant Diabetic Macular Edema: Doi: 10.36351/pjo.v39i1.1480 JF - Pakistan Journal of Ophthalmology JA - pak J Ophthalmol VL - 39 IS - 1 SE - Original Articles DO - 10.36351/pjo.v39i1.1480 UR - https://pjo.org.pk/index.php/pjo/article/view/1480 SP - AB - <p><strong>Purpose:</strong>  To compare the effectiveness and safety of suprachoroidal versus intravitreal Triamcinolone Acetonide in cases of resistant diabetic macular edema.</p><p><strong>Study Design:</strong>  Quasi experimental study.</p><p><strong>Place and Duration of Study:</strong>  This research was executed at Retina Department of Al-Ibrahim Eye Hospital, Karachi, Pakistan between 1<sup>st</sup> January 2022 till 30<sup>th</sup> June 2022.</p><p><strong>Methods:</strong>  Thirty-four patients with resistant diabetic macular edema were selected through convenient sampling and divided equally into two groups. All patients underwent ocular examination. Group I was given single Intravitreal injection (IVI) of 0.1 mL Triamcinolone Acetonide at 4 mg per 0.1 mL concentration. Group II received same dosage of drug via Suprachoroidal injection (SCI). After 24 hours, they were assessed for side effects. After 6 weeks, second dose of same drug was administered. Patients were followed at 3 and 6 months.</p><p><strong>Results:</strong>  No serious side effect was observed in any patient within 24 hours. At 1 month follow-up period, comparison between the two groups for BCVA, CMT and IOP was not significant (p &gt; 0.05). When the two groups were compared at 3 months, both routes were equally effective but IOP remained more stable via SCI route. At 6 months, IOP remained elevated in group I but decreased in group II (p = 0.003).</p><p><strong>Conclusion:</strong>  Triamcinolone Acetonide was effective by both routes in resistant diabetic macular edema in terms of improved BCVA and CMT but SCI was better in terms of IOP and cataract progression.</p> ER -