TY - JOUR AU - idris, Mohammad AU - Yaqoob, Hassan AU - Khan, Muhammad Adnan AU - Zar, Adnan AU - Alam, Muhib ul PY - 2021/02/22 Y2 - 2024/03/19 TI - Demographic Characteristics and Causes of Acquired Non-senile Ptosis: Experience at a Tertiary Oculoplastic Center: http://doi.org/10.36351/pjo.v37i2.1173 JF - Pakistan Journal of Ophthalmology JA - pak J Ophthalmol VL - 37 IS - 2 SE - Original Articles DO - 10.36351/pjo.v37i2.1173 UR - https://pjo.org.pk/index.php/pjo/article/view/1173 SP - AB - <p><strong>Purpose:&nbsp;&nbsp;</strong>To determine the demographic characteristics and causes of acquired, non-senile ptosis in patients presenting to an oculoplastic clinic of a tertiary care centre.</p><p><strong>Study Design:&nbsp;&nbsp;</strong>Observational case series.</p><p><strong>Place and Duration of Study:</strong> Lady Reading Hospital, from January 2016 to December 2017.</p><p><strong>Methods:&nbsp;&nbsp;</strong>Twenty eight patients were fulfilling the inclusion criteria were recruited in the study. Detailed history with complete examination and investigations like electromyography, acetylcholine receptor antibody test and CT/MRI brain were performed when required. Cause of each ptosis was determined and the relative proportions were calculated.</p><p><strong>Results:</strong>&nbsp;&nbsp;There were 28 cases with acquired, non-senile ptosis. Fifty seven percent were males while females were 42.9%. Patients were divided into four age groups. Most of the patients were in age group of 42–62 years. Eyelid/orbit tumor and Chronic progressive external ophthalmoplegia (CPEO) was seen in <strong>3.6%</strong> and <strong>7.1%</strong> patients of &lt; 20 years of age respectively. Myasthenia gravis and thyroid related pseudoptosis was common in patients of 21-41 years. In patients with age 42-62 years, Pseudoptosis due to thyroid disorder was the commonest. In patients with age more than 63 years, 3<sup>rd</sup> nerve palsy, eyelid/orbital mass and Myasthenia gravis was seen. Third nerve palsy and Pseudoptosis secondary to thyroid and eyelid/orbit mass were more common in males while Myasthenia gravis was more common in females. CPEO was equally seen in both genders with<br> p = 0.575.</p><p><strong>Conclusion:&nbsp;&nbsp;</strong>Thyroid related eyelid pseudoptosis of the contralateral eye was the commonest cause in this case series.</p><p><strong>Key Words:&nbsp;&nbsp;</strong>Blepharoptosis, Third nerve palsy, Myasthenia gravis.</p> ER -