@article{idris_Yaqoob_Khan_Zar_Alam_2021, title={Demographic Characteristics and Causes of Acquired Non-senile Ptosis: Experience at a Tertiary Oculoplastic Center: http://doi.org/10.36351/pjo.v37i2.1173}, volume={37}, url={https://pjo.org.pk/index.php/pjo/article/view/1173}, DOI={10.36351/pjo.v37i2.1173}, abstractNote={<p><strong>Purpose:  </strong>To determine the demographic characteristics and causes of acquired, non-senile ptosis in patients presenting to an oculoplastic clinic of a tertiary care centre.</p> <p><strong>Study Design:  </strong>Observational case series.</p> <p><strong>Place and Duration of Study:</strong> Lady Reading Hospital, from January 2016 to December 2017.</p> <p><strong>Methods:  </strong>Twenty eight patients were fulfilling the inclusion criteria were recruited in the study. Detailed history with complete examination and investigations like electromyography, acetylcholine receptor antibody test and CT/MRI brain were performed when required. Cause of each ptosis was determined and the relative proportions were calculated.</p> <p><strong>Results:</strong>  There were 28 cases with acquired, non-senile ptosis. Fifty seven percent were males while females were 42.9%. Patients were divided into four age groups. Most of the patients were in age group of 42–62 years. Eyelid/orbit tumor and Chronic progressive external ophthalmoplegia (CPEO) was seen in <strong>3.6%</strong> and <strong>7.1%</strong> patients of < 20 years of age respectively. Myasthenia gravis and thyroid related pseudoptosis was common in patients of 21-41 years. In patients with age 42-62 years, Pseudoptosis due to thyroid disorder was the commonest. In patients with age more than 63 years, 3<sup>rd</sup> nerve palsy, eyelid/orbital mass and Myasthenia gravis was seen. Third nerve palsy and Pseudoptosis secondary to thyroid and eyelid/orbit mass were more common in males while Myasthenia gravis was more common in females. CPEO was equally seen in both genders with<br> p = 0.575.</p> <p><strong>Conclusion:  </strong>Thyroid related eyelid pseudoptosis of the contralateral eye was the commonest cause in this case series.</p> <p><strong>Key Words:  </strong>Blepharoptosis, Third nerve palsy, Myasthenia gravis.</p>}, number={2}, journal={Pakistan Journal of Ophthalmology}, author={idris, Mohammad and Yaqoob, Hassan and Khan, Muhammad Adnan and Zar, Adnan and Alam, Muhib ul}, year={2021}, month={Feb.} }